Award Date


Degree Type

Doctoral Project

Degree Name

Doctor of Nursing (ND)



First Committee Member

Jennifer Vanderlaan

Second Committee Member

Necole Leland

Third Committee Member

Jay Shen

Number of Pages



Central line-associated bloodstream infections (CLABSI) are a rising problem in the critical care setting in the United States. According to Flogren et al. (2007), "an estimated 248,000 bloodstream infections occur in hospitals across the United States each year, and a significant amount of these infections are associated with the use of a central venous catheter" (p.160). The Center for Disease Control and Prevention (CDC) defines a CLABSI as "recovery of a pathogen from blood culture (a single blood culture for organisms not commonly present on the skin and two or more blood cultures for organisms commonly present on the skin) in a patient who had a central line at the time of infection or within the 48 hours before the development of infection" ("Vital Signs: Central Line-Associated Blood Stream Infections—United States, 2001, 2008, and 2009," 2011, p. 447). After forty-eight hours, the development of a CLABSI most often points to infection attributed to central line placement or maintenance. The U.S. Department of Health and Human Services noted CLABSIs as a significant concern and, in 2009, set a national goal for a 50% reduction in CLABSIs by 2013 (Wise et al., 2013). Since then, however, hospital systems across the United States have been challenged with meeting this goal. This project aims to improve the efficacy of the CLABSI bundle currently used in the critical care setting by implementing nursing interventions supported by evidence-based practice that will help prevent the incidence of CLABSI in the acute care patient population.

Controlled Subject

Bloodborne infections--Prevention;Intensive care units;Intravenous catheterization



File Format


File Size

2400 KB

Degree Grantor

University of Nevada, Las Vegas




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Included in

Nursing Commons