Base-Controlled Fe(Pc)-Catalyzed Aerobic Oxidation of Thiols for the Synthesis of S-S and S-P(O) Bonds
Document Type
Article
Publication Date
5-17-2018
Publication Title
Organic and Biomolecular Chemistry
Volume
16
Issue
23
First page number:
4236
Last page number:
4242
Abstract
Fe(Pc)-Catalyzed aerobic oxidation of thiols for the synthesis of disulfides has been developed under mild reaction conditions. In addition, an aerobic oxidative cross-dehydrogenative coupling (CDC) reaction of thiols with P(O)–H compounds (H-phosphonates and H-phosphine oxide) for the formation of S–P(O) bonds has been demonstrated under the Fe(Pc) catalysis system with a base additive. Control experiments revealed that the use of a base (DIPA) in this system controls the synthetic pathways in which thiophosphates are formed.
Disciplines
Organic Chemistry
File Format
File Size
1060 KB
Language
English
Repository Citation
Huang, H.,
Ash, J.,
Kang, J. Y.
(2018).
Base-Controlled Fe(Pc)-Catalyzed Aerobic Oxidation of Thiols for the Synthesis of S-S and S-P(O) Bonds.
Organic and Biomolecular Chemistry, 16(23),
4236-4242.
http://dx.doi.org/10.1039/C8OB00908B
